Diethyl cyanophosphonate → HCID 86758866, compound

Participants

Reaction Steps

In a similar manner to that described in Example 73, a reaction was carried out using 2-trimethylsilylethyl (R)-3-[4-(2-t-butoxycarbonylaminoethoxy)phenyl]-2-(4-isopropylphenoxy)propionate (356 mg), 4-pyridine-2-ylbenzoic acid (143 mg), diethyl cyanophosphonate (0.11 ml) and triethylamine (0.10 ml) and the reaction mixture was treated to afford the title compound (307 mg) as a colorless oil.

Provenance & Evidence