Sodium Hydroxide → HCID 18625786, compound

HRID 1860056Notes

Reaction equation

HRID 1860056 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[N:5][C:6]([C:9]2[CH:18]=[CH:17][CH:16]=[CH:15][C:10]=2[C:11]([O:13]C)=[O:12])=[CH:7][CH:8]=1.[OH-].[Na+]>>[CH3:1][O:2][C:3]1[CH:4]=[N:5][C:6]([C:9]2[CH:18]=[CH:17][CH:16]=[CH:15][C:10]=2[C:11]([OH:13])=[O:12])=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 18626010HCID 18626010, compound

Product 1

HCID 18625786HCID 18625786, compoundYield 87.8%

Procedure

In a similar manner to that described in Example 2, a reaction was carried out using methyl 3-methoxypyridine-6-ylbenzoate (249 mg), which is the product of Reference example 33(b), and aqueous sodium hydroxide solution (1N, 1.20 ml) and the reaction mixture was treated to afford the title compound (206 mg) as colorless crystals.

Workup

  1. additionthe reaction mixture was treated

Sources & evidence

ORD record
ord-3e9b2ff0727940dfaf811fcd52c43b17
Source dataset
uspto-grants-2003_03
Patent number
US06528525B1

Reaction notes

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