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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860061Generated: November 2, 2026

Potassium Carbonate → Ethyl 3-[4-(2-t-butoxycarbonylaminoethoxy)phenyl]-2-(4-methylphenoxy)propionate

https://huagongshe.com/reaction/1860061

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantEthyl 3-(4-hydroxyphenyl)-2-(4-methylphenoxy)propionateHCID 18626029—
Reactanttert-Butyl N-(2-((methylsulfonyl)oxy)ethyl)carbamateHCID 22605302—
ProductEthyl 3-[4-(2-t-butoxycarbonylaminoethoxy)phenyl]-2-(4-methylphenoxy)propionateHCID 1862585858.9%

Reaction Steps

In a similar manner to that described in Reference example 25, a reaction was carried out using ethyl 3-(4-hydroxyphenyl)-2-(4-methylphenoxy)propionate (300 mg), which is the-product of Reference example 35(c), t-butyl 2-methanesulfonyloxy-ethylcarbamate (598 mg) and potassium carbonate (691 mg) and the reaction mixture was treated to afford the title compound (261 mg) as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-18e5092098d148debc4511b610eed4c0
Source noteuspto-grants-2003_03