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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860063Generated: October 30, 2026

Ethyl 3-(4-benzyloxyphenyl)-2-(4-t-butylphenoxy)propionate → Ethyl 2-(4-t-butylphenoxy)-3-(4-hydroxyphenyl)propionate

https://huagongshe.com/reaction/1860063

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 3-(4-benzyloxyphenyl)-2-(4-t-butylphenoxy)propionateHCID 18625918—
CatalystPalladiumHCID 23938—
ProductEthyl 2-(4-t-butylphenoxy)-3-(4-hydroxyphenyl)propionateHCID 1862593899.8%

Reaction Steps

In a similar manner to that described in Reference example 1(d), a reaction was carried out using ethyl 3-(4-benzyloxyphenyl)-2-(4-t-butylphenoxy)propionate (3.00 g), which is the product of Reference example 36(a) and palladium on carbon (5%, 300 mg) and the reaction mixture was treated to afford the desired compound (2.37 g) as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-b38173c374344748aa6df668826cb241
Source noteuspto-grants-2003_03