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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860064Generated: October 30, 2026

Potassium Carbonate → Ethyl 3-[4-(2-t-butoxycarbonylaminoethoxy)phenyl]-2-(4-t-butylphenoxy)propionate

https://huagongshe.com/reaction/1860064

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantEthyl 2-(4-t-butylphenoxy)-3-(4-hydroxyphenyl)propionateHCID 18625938—
Reactanttert-Butyl N-(2-((methylsulfonyl)oxy)ethyl)carbamateHCID 22605302—
ProductEthyl 3-[4-(2-t-butoxycarbonylaminoethoxy)phenyl]-2-(4-t-butylphenoxy)propionateHCID 1862572793.1%

Reaction Steps

In a similar manner to that described in Reference example 25, a reaction was carried out using ethyl 2-(4-t-butylphenoxy)-3-(4-hydroxyphenyl)propionate (2.37 g), which is the product of Reference example 36(b), t-butyl 2-methanesulfonyloxyethylcarbamate (3.60 g) and potassium carbonate (4.78 g) and the reaction mixture was treated to afford the title compound (3.13 g) as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-5df65490277745dab4b78f2e6d45d5f8
Source noteuspto-grants-2003_03