HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenol → HCID 18625833, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenol | HCID 9732 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Diethyl azodicarboxylate | HCID 5462977 | — |
| Reactant | 3-(4-Benzyloxyphenyl)-2-hydroxypropionic acid ethyl ester | HCID 15186153 | — |
| Product | HCID 18625833 | HCID 18625833 | 53.3% |
Reaction Steps
In a similar manner to that described in Example 122, a reaction was carried out using ethyl 3-(4-benzyloxyphenyl)lactate (10.0 g), which is the product of Reference example 1(b), 4-fluorophenol (4.15 g), triphenylphosphine (10.6 g) and diethylazodicarboxylate (6.40 ml) and the reaction mixture was treated to afford the desired compound (7.00 g) as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528525B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-f1510a51d394480b9bc744bd94322bdc |
| Source note | uspto-grants-2003_03 |