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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860080Generated: October 30, 2026

Ethyl 3-(4-benzyloxyphenyl)-2-(4-cyanophenoxy)propionate → Ethyl 2-(4-cyanophenoxy)-3-(4-hydroxyphenyl)propionate

https://huagongshe.com/reaction/1860080

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 3-(4-benzyloxyphenyl)-2-(4-cyanophenoxy)propionateHCID 18626028—
CatalystPalladiumHCID 23938—
ProductEthyl 2-(4-cyanophenoxy)-3-(4-hydroxyphenyl)propionateHCID 18625868100.5%

Reaction Steps

In a similar manner to that described in Reference example 1(d), a reaction was carried out using ethyl 3-(4-benzyloxyphenyl)-2-(4-cyanophenoxy)propionate (376 mg), which is the product of Reference example 41(a), and palladium on carbon (5%, 65 mg) and the reaction mixture was treated to afford the title compound (293 mg) as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-6e23ce9faecc43f4a42d8076e5a72c53
Source noteuspto-grants-2003_03