4-Fluorophenol → HCID 18625854, compound

Participants

Reaction Steps

In a similar manner to that described in Example 122, a reaction was carried out using methyl 3-[4-(2-t-butoxycarbonylaminoethoxy)phenyl]-2-hydroxypropionate (420 mg), which is obtained in a similar manner to that described in Reference example 39(a), 4-fluorophenol (284 mg), triphenylphosphine (666 mg) and solution of diethylazodicarboxylate in toluene (40%, 1.10 ml) and the reaction mixture was treated to afford the desired compound (314 mg) as a colorless oil.

Provenance & Evidence