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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860088Generated: November 2, 2026

Benzyl Bromide → HCID 18625871, compound

https://huagongshe.com/reaction/1860088

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
ReactantHydrideHCID 166653—
ReactantHCID 18625783HCID 18625783—
CatalystTetrabutylammonium IodideHCID 67553—
ProductHCID 18625871HCID 18625871—

Reaction Steps

In a similar manner to that described in Reference example 1(c), a reaction was carried out using methyl 3-[4-(2-t-butoxycarbonylaminoethoxy)phenyl]-2-hydroxypropionate (398 mg), which is obtained in a similar manner to that described in Reference example 39(a), benzylbromide (0.28 ml), hydride (55% suspension in oil, 168 mg) and tetrabutylammonium iodide (43 mg) and the reaction mixture was treated to afford the desired compound (133 mg) as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-42a3bb80f2354eed97a1786925a6a9d8
Source noteuspto-grants-2003_03