HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 86590722, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | N-[(Phenylmethoxy)carbonyl]-L-tyrosine methyl ester | HCID 7010613 | — |
| Reactant | tert-Butyl N-(2-((methylsulfonyl)oxy)ethyl)carbamate | HCID 22605302 | — |
| Product | HCID 86590722 | HCID 86590722 | 46.8% |
Reaction Steps
In a similar manner to that described in Reference example 25, a reaction was carried out using N-benzyloxycarbonyl-L-tyrosine methyl ester (4.94 g), t-butyl 2-methanesulfonyloxyethylcarbamate (8.97 g) and potassium carbonate (10.4 g) and the reaction mixture was treated to afford the title compound (3.32 g) as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528525B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-d3a2f958240241d2b2c833f8388e52ec |
| Source note | uspto-grants-2003_03 |