HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+-)-1-Aminoindan → (Rac)-n-(4-(di-n-propylsulfamoyl)benzoyl)-1-aminoindan
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+-)-1-Aminoindan | HCID 123445 | — |
| Reactant | 4-(Dipropylsulfamoyl)benzoyl chloride | HCID 2735528 | — |
| Product | (Rac)-n-(4-(di-n-propylsulfamoyl)benzoyl)-1-aminoindan | HCID 18627820 | 63% |
Reaction Steps
The title compound was prepared in 63% yield from (rac)-1-aminoindan (10.0 g, 75.2 mmole) and 4-(di-n-propylsulfamoyl) benzoyl chloride (16.3 g, 53.6 mmole, prepared from probenecid and SOCl2) via a procedure analogous to that described in Ex. 46, followed by crystallization from hexane:EtOAc, mp: 124-5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528685B2 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-2a497d5ae13d4fe0986d91ab0cca90e2 |
| Source note | uspto-grants-2003_03 |