HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dopamine Hydrochloride → HCID 22976108, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dopamine Hydrochloride | HCID 65340 | — |
| Reactant | L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- | HCID 1549483 | — |
| Product | HCID 22976108 | HCID 22976108 | 120.1% |
Reaction Steps
The title compound was prepared from Nα-(tert-butoxycarbonyl)-O-benzyl-L-threonine (2.0 g, 6.5 mmol) following the indications of general procedure F using dopamine hydrochloride (2.4 g, 9.7 mmol). The crude material was purified by flash chromatography eluting with 30% EtOAc/CHCl3 to give 2.8 g (98%) of the desired product as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528655B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-656e226b4bcd492d93fcc5b8a9674158 |
| Source note | uspto-grants-2003_03 |