1-(4-Tolyl)-3-(4-nitrophenyl)-5-aminopyrazole → 5-(4-Amino-phenyl)-2-p-tolyl-2H-pyrazol-3-ylamine

Participants

Reaction Steps

To a solution of 1-(4-tolyl)-3-(4-nitrophenyl)-5-aminopyrazole (0.48 g, 1.6 mmol) in EtOAc (50 mL) at room temperature was added 10% Pd-C (0.1 g). The mixture was treated with hydrogen gas at 30 psi for 30 min. on a Parr shaker. The mixture was filtered through Celite and the solvent removed by rotary evaporation to yield 1-(4-tolyl)-3-(4-aminophenyl)-5-aminopyrazole as an oil, which was used without further purification.

Provenance & Evidence