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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860604Generated: October 31, 2026

Phenethylamine → 2'-Phthalimidomethylbiphenyl-2-carboxylic acid phenethylamide

https://huagongshe.com/reaction/1860604

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenethylamineHCID 1001—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant2'-Phthalimidomethylbiphenyl-2-carboxylic acidHCID 14258571—
Product2'-Phthalimidomethylbiphenyl-2-carboxylic acid phenethylamideHCID 67317708—

Reaction Steps

From 2′-phthalimidomethylbiphenyl-2-carboxylic acid (precursor 2), after activation with CDI and reaction with phenethylamine, 2′-phthalimidomethylbiphenyl-2-carboxylic acid phenethylamide was obtained; m.p. 156° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06531495B1
Source datasetuspto-grants-2003_03
ORD IDord-ba3a00cde04843c09865d4676d4e0d6c
Source noteuspto-grants-2003_03