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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860621Generated: October 26, 2026

5-(Piperazin-1-yl)benzofuran-2-carboxamide → Vilazodone

https://huagongshe.com/reaction/1860621

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Piperazin-1-yl)benzofuran-2-carboxamideHCID 9834719—
Reactant3-(4-Chlorobutyl)-5-cyanoindoleHCID 9881123—
ProductVilazodoneHCID 6918314—

Reaction Steps

in that 5-(1-piperazinyl)benzofuran-2-carboxamide is reacted with 3-(4-chlorobutyl)-5-cyanoindole to give 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)piperazine and

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06531503B1
Source datasetuspto-grants-2003_03
ORD IDord-e93e5314ea4d4fc3b7855f967dff88b7
Source noteuspto-grants-2003_03