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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860729Generated: October 31, 2026

Dimethylformamide → 3-(2-Formyl-5-methyl-1H-pyrrol-3-yl)propanoic acid

https://huagongshe.com/reaction/1860729

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantPhosphorus oxychlorideHCID 24813—
Reactant3-(5-Methyl-1H-pyrrol-3-yl)propanoic acidHCID 13310352—
Product3-(2-Formyl-5-methyl-1H-pyrrol-3-yl)propanoic acidHCID 22135394—

Reaction Steps

3-(5-Methyl-1H-pyrrole-3-yl)propionic acid was formylated using phosphorus oxycloride (POCl3) and N,N-dimethylformamide (DMF) to give 3-(2-formyl-5-methyl-1H-pyrrole-3-yl)propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06531502B1
Source datasetuspto-grants-2003_03
ORD IDord-f4e79b0fb0a44212be2971617bf21254
Source noteuspto-grants-2003_03