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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860752Generated: October 25, 2026

Oxindole → 3-(3-Isopropyl-4-methoxybenzylidene)-1,3-dihydroindol-2-one

https://huagongshe.com/reaction/1860752

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxindoleHCID 321710—
Reactant3-Isopropyl-4-methoxybenzaldehydeHCID 9898990—
Product3-(3-Isopropyl-4-methoxybenzylidene)-1,3-dihydroindol-2-oneHCID 53799055—

Reaction Steps

2-Isopropylphenol was methylated and then formylated to give 3-isopropyl-4-methoxybenzaldehyde. 3-Isopropyl-4-methoxybenzaldehyde was condensed with 2-oxindole to give 0.3 g of 3-(3-isopropyl-4-methoxybenzylidene)-1,3-dihydroindol-2-one as a yellow-orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06531502B1
Source datasetuspto-grants-2003_03
ORD IDord-c468de827b5141e69ebb94a77083b0db
Source noteuspto-grants-2003_03