Oxindole → 3-(5-Isopropyl-4-methoxy-2-methylbenzylidene)-1,3-dihydroindol-2-one

HRID 1860753Notes

Reaction equation

[CH:1]([C:4]1[C:5]([O:13][CH3:14])=[CH:6][C:7]([CH3:12])=[C:8]([CH:11]=1)[CH:9]=O)([CH3:3])[CH3:2].[NH:15]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH2:17][C:16]1=[O:24]>>[CH:1]([C:4]1[C:5]([O:13][CH3:14])=[CH:6][C:7]([CH3:12])=[C:8]([CH:11]=1)[CH:9]=[C:17]1[C:18]2[C:23](=[CH:22][CH:21]=[CH:20][CH:19]=2)[NH:15][C:16]1=[O:24])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 321710Oxindole

HCID 32761295-Isopropyl-4-methoxy-2-methylbenzaldehyde

Product 1

HCID 540844983-(5-Isopropyl-4-methoxy-2-methylbenzylidene)-1,3-dihydroindol-2-one

Procedure

5-Isopropyl-4-methoxy-2-methylbenzaldehyde was condensed with 2-oxindole to give 0.25 g of 3-(5-Isopropyl-4-methoxy-2-methylbenzylidene)-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record: ord-ab0669d8761041a792c26915d3cbfebd
Source dataset: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06531502B1

Reaction notes

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