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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860793Generated: October 25, 2026

5-fluoro-1,3-dihydro-2H-indol-2-one → 5-Fluoro-3-(6-methoxybiphenyl-3-ylmethylene)-1,3-dihydroindol-2-one

https://huagongshe.com/reaction/1860793

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-fluoro-1,3-dihydro-2H-indol-2-oneHCID 3731012—
Reactant6-Methoxybiphenyl-3-carbaldehydeHCID 22391217—
Product5-Fluoro-3-(6-methoxybiphenyl-3-ylmethylene)-1,3-dihydroindol-2-oneHCID 53639002—

Reaction Steps

4-Methoxy-3-phenylbenzaldehyde was condensed with 5-fluoro-2-oxindole to give 0.3 g of 5-fluoro-3-(6-methoxybiphenyl-3-ylmethylene)-1,3-dihydroindol-2-one as a yellow-orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06531502B1
Source datasetuspto-grants-2003_03
ORD IDord-14a5e624cb4241f6a11e429f528f6763
Source noteuspto-grants-2003_03