2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-6-carbaldehyde → 3-(2,2-Dimethylchroman-6-ylmethylene)-4-methyl-1,3-dihydroindol-2-one

HRID 1860796Notes

Reaction equation

HRID 1860796 reaction equation
[CH3:1][C:2]1([CH3:14])[CH2:11][CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH:12]=O)[CH:8]=2)[O:3]1.[CH3:15][C:16]1[CH:24]=[CH:23][CH:22]=[C:21]2[C:17]=1[CH2:18][C:19](=[O:25])[NH:20]2>>[CH3:1][C:2]1([CH3:14])[CH2:11][CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH:12]=[C:18]3[C:17]4[C:21](=[CH:22][CH:23]=[CH:24][C:16]=4[CH3:15])[NH:20][C:19]3=[O:25])[CH:8]=2)[O:3]1

Participants

3

Reactant 2

HCID 17977512,2-dimethyl-3,4-dihydro-2H-1-benzopyran-6-carbaldehydeHCID 125793824-Methyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 538195253-(2,2-Dimethylchroman-6-ylmethylene)-4-methyl-1,3-dihydroindol-2-one

Procedure

2,2-Dimethyl-6-formylchromane (commercially available) was condensed with 4-methyl-2-oxindole to give 0.25 g of 3-(2,2-dimethylchroman-6-ylmethylene)-4-methyl-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record
ord-b6a28469e33e44109ae81c4bfcaf0289
Source dataset
uspto-grants-2003_03
Patent number
US06531502B1

Reaction notes

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