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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860798Generated: October 26, 2026

5-fluoro-1,3-dihydro-2H-indol-2-one → 5-Fluoro-3-(3-isopropyl-4-methoxybenzylidene)-1,3-dihydroindol-2-one

https://huagongshe.com/reaction/1860798

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-fluoro-1,3-dihydro-2H-indol-2-oneHCID 3731012—
Reactant3-Isopropyl-4-methoxybenzaldehydeHCID 9898990—
Product5-Fluoro-3-(3-isopropyl-4-methoxybenzylidene)-1,3-dihydroindol-2-oneHCID 54324035—

Reaction Steps

3-Isopropyl-4-methoxybenzaldehyde was condensed with 5-fluoro-2-oxindole to give 0.25 g of 5-fluoro-3-(3-isopropyl-4-methoxybenzylidene)-1,3-dihydroindol-2-one as a yellow-orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06531502B1
Source datasetuspto-grants-2003_03
ORD IDord-61185c9213db43a58b24981f999c06ab
Source noteuspto-grants-2003_03