3,5-Diisopropyl-4-methoxybenzaldehyde → 7-Chloro-3-(3,5-diisopropyl-4-methoxybenzylidene)-5-methyl-1,3-dihydroindol-2-one

HRID 1860844Notes

Reaction equation

HRID 1860844 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=O)([CH3:3])[CH3:2].[CH3:17][C:18]1[CH:19]=[C:20]2[C:24](=[C:25]([Cl:27])[CH:26]=1)[NH:23][C:22](=[O:28])[CH2:21]2>>[Cl:27][C:25]1[CH:26]=[C:18]([CH3:17])[CH:19]=[C:20]2[C:24]=1[NH:23][C:22](=[O:28])[C:21]2=[CH:7][C:6]1[CH:5]=[C:4]([CH:1]([CH3:3])[CH3:2])[C:11]([O:12][CH3:13])=[C:10]([CH:14]([CH3:16])[CH3:15])[CH:9]=1

Participants

3

Reactant 2

HCID 105850253,5-Diisopropyl-4-methoxybenzaldehydeHCID 534189105-Methyl-7-chloro-2-oxindole

Product 1

HCID 544504847-Chloro-3-(3,5-diisopropyl-4-methoxybenzylidene)-5-methyl-1,3-dihydroindol-2-one

Procedure

3,5-Diisopropyl-4-methoxybenzaldehyde was condensed with 5-methyl-7-chloro-2-oxindole to give 0.35 g of 7-chloro-3-(3,5-diisopropyl-4-methoxybenzylidene)-5-methyl-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record
ord-21ea66a356e949ea8bd7fa022d85a4f2
Source dataset
uspto-grants-2003_03
Patent number
US06531502B1

Reaction notes

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