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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860876Generated: October 25, 2026

N-methyl-2-oxoindoline-5-sulfonamide → 3-[3-(3-Dimethylaminopropyl)-1H-indol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic Acid Methyl Amide

https://huagongshe.com/reaction/1860876

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-oxoindoline-5-sulfonamideHCID 10176909—
Reactant3-(3-dimethylaminopropyl)-1H-indole-2-carbaldehydeHCID 22571054—
Product3-[3-(3-Dimethylaminopropyl)-1H-indol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic Acid Methyl AmideHCID 69769741—

Reaction Steps

2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide (98 mg, 0.43 mmol) was condensed with 3-(3-dimethylaminopropyl)-1H-indole-2-carbaldehyde (100 mg) to give the title compound as an orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06531502B1
Source datasetuspto-grants-2003_03
ORD IDord-85b4d090a012468f8f391c49e14d42e2
Source noteuspto-grants-2003_03