HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 1,3-Di-cyclohexyl-8-chloro xanthine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 1,3-Di-cyclohexyl-8-nitro xanthine | HCID 9968896 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1,3-Di-cyclohexyl-8-chloro xanthine | HCID 9924570 | — |
Reaction Steps
1,3-Di-cyclohexyl-8-chloro xanthine was prepared from 1,3-di-cyclohexyl-8-nitro xanthine (2 g, 0.006 mol) and phosphorus oxychloride (3.9 g) in dimethylformamide (6 ml), using an analogous procedure to that described in Example 17. The product was obtained as a crystalline product after recrystallisation from ethyl acetate, m.pt., 135° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06531600B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-10e34a9b61b747b3910bd5290554266d |
| Source note | uspto-grants-2003_03 |