Water → 2-Chloropyridine-3-sulfonyl chloride

HRID 1861026Notes

Reaction equation

N[C:2]1[C:3]([Cl:8])=[N:4][CH:5]=[CH:6][CH:7]=1.[S:9]([Cl:12])(Cl)=[O:10].[OH2:13]>>[Cl:8][C:3]1[C:2]([S:9]([Cl:12])(=[O:10])=[O:13])=[CH:7][CH:6]=[CH:5][N:4]=1

Participants

Reactant 3

HCID 962Water

HCID 24386Thionyl Chloride

HCID 805282-Chloro-3-pyridylamine

Product 1

HCID 102199682-Chloropyridine-3-sulfonyl chloride

Procedure

reaction of the diazonium salt of 3-amino-2-chloropyridine with a mixture of thionyl chloride in water, in the presence of an electron transfer catalyst, to give 2-chloropyridine-3-sulfonyl chloride;

Sources & evidence

ORD record: ord-a693d39f90ab4dbba8ee28297bf164bd
Source dataset: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06531605B1

Reaction notes

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