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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 186127Generated: October 25, 2026

1,1'-Carbonyldiimidazole → 3,4-difluoro-2-{2-fluoro-4-[4-(tetrahydro-2H-pyran-2-yloxy)-1-butynyl]anilino}-N-(2-hydroxyethoxy)benzamide

https://huagongshe.com/reaction/186127

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantEthanol, 2-(aminooxy)-HCID 3014186—
Reactant3,4-difluoro-2-{2-fluoro-4-[4-(tetrahydro-2H-pyran-2-yloxy)-1-butynyl]anilino}benzoic AcidHCID 22025642—
Product3,4-difluoro-2-{2-fluoro-4-[4-(tetrahydro-2H-pyran-2-yloxy)-1-butynyl]anilino}-N-(2-hydroxyethoxy)benzamideHCID 22025628—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-1b5bf19d2c1341c7bccf2d7f765d76ae
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)