HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2,2,2-trichloroacetimidate → 5-Fluoro-2-trichloromethyl-1H-benzoimidazole-4-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2,2,2-trichloroacetimidate | HCID 100479 | — |
| Reactant | HCID 58101800 | HCID 58101800 | — |
| Product | 5-Fluoro-2-trichloromethyl-1H-benzoimidazole-4-carboxylic acid ethyl ester | HCID 68617326 | — |
Reaction Steps
5-Fluoro-2-trichloromethyl-1H-benzoimidazole-4-carboxylic acid ethyl ester was prepared by a procedure according to example 5 (i) starting from 150.0 mg (0.76 mmol) 2,3-Diamino-6-fluoro-benzoic acid ethyl ester and 133 μl (1.06 mmol) 2,2,2-trichloro-acetimidic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07741341B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-645f30d875364c4f8877808e6fce07c8 |
| Source note | uspto-grants-2010_06 |