HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloranil → HCID 15871130, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloranil | HCID 8371 | — |
| Reactant | HCID 15871129 | HCID 15871129 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | HCID 15871130 | HCID 15871130 | — |
Reaction Steps
1 g of 17β-hydroxy-14β,15β-methylen-androst-4-en-3-one (production, Example 2) is refluxed with 1.2 g of chloranil in 50 ml of tert-butanol for 30 minutes. It is allowed to cool and evaporated to the dry state. The residue is chromatographed on silica gel (mobile solvent: dichloromethane/ethyl acetate 10:1). For further purification, it is recrystallized from ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06534490B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-6040d38970e64d6187ba229c178c4a5a |
| Source note | uspto-grants-2003_03 |