HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piroctone → Ciclopirox
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piroctone | HCID 50259 | — |
| Reactant | 3-(2-phenylethyl)pyridin-2(1h)-one | HCID 268034 | — |
| Reactant | HCID 22223091 | HCID 22223091 | — |
| Product | Ciclopirox | HCID 2749 | — |
Reaction Steps
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone, 1-hydroxy-4-methyl-6-n-hexyl, -6-iso-hexyl-, 6-n-heptyl- or -6-isoheptyl-2-pyridone, 1-hydroxy-4-methyl-6-octyl- or -6-isooctyl-2-pyridone, in particular 1-hydroxy-4-methyl-6-cyclohexylmethyl- or 6-cyclohexylethyl-2-pyridone, it being possible for the cyclohexyl radical in each case also to carry a methyl radical, 1-hydroxy-4-methyl-6-(2-bicyclo[2,2,1]heptyl)-2-pyridone, 1-hydroxy-3,4-dimethyl-6-benzyl- or -6-dimethylbenzyl-2-pyridone or 1-hydroxy-4-methyl-6-(β-phenylethyl-2-pyridone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06534528B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-e1cd9d0c3d044f60aab22cb8cb6b59bb |
| Source note | uspto-grants-2003_03 |