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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1861752Generated: November 1, 2026

Piroctone → Ciclopirox

https://huagongshe.com/reaction/1861752

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiroctoneHCID 50259—
Reactant3-(2-phenylethyl)pyridin-2(1h)-oneHCID 268034—
ReactantHCID 22223091HCID 22223091—
ProductCiclopiroxHCID 2749—

Reaction Steps

1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone, 1-hydroxy-4-methyl-6-n-hexyl, -6-iso-hexyl-, 6-n-heptyl- or -6-isoheptyl-2-pyridone, 1-hydroxy-4-methyl-6-octyl- or -6-isooctyl-2-pyridone, in particular 1-hydroxy-4-methyl-6-cyclohexylmethyl- or 6-cyclohexylethyl-2-pyridone, it being possible for the cyclohexyl radical in each case also to carry a methyl radical, 1-hydroxy-4-methyl-6-(2-bicyclo[2,2,1]heptyl)-2-pyridone, 1-hydroxy-3,4-dimethyl-6-benzyl- or -6-dimethylbenzyl-2-pyridone or 1-hydroxy-4-methyl-6-(β-phenylethyl-2-pyridone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06534528B1
Source datasetuspto-grants-2003_03
ORD IDord-e1cd9d0c3d044f60aab22cb8cb6b59bb
Source noteuspto-grants-2003_03