Allyl bromide → HCID 178419556, compound

HRID 1861904Notes

Reaction equation

[C:1]([O:5][C:6](=[O:19])[NH:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([NH:15][C:16]([NH2:18])=[S:17])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].[CH2:20]([Br:23])[CH:21]=[CH2:22]>>[BrH:23].[C:1]([O:5][C:6](=[O:19])[NH:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([NH:15][C:16](=[NH:18])[S:17][CH2:22][CH:21]=[CH2:20])[CH:10]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

Reactant 2

HCID 7841Allyl bromide

HCID 18331431HCID 18331431, compound

Product 1

HCID 178419556HCID 178419556, compoundYield 34%

Procedure

Using the compound obtained in Example 24 as a starting material and also using allyl bromide as a reagent, the same procedure of Example 4 gave 118 mg of the titled compound (yield, 34%).

Sources & evidence

ORD record: ord-e377148008924c1dbab629d5855b3b40
Source dataset: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06534546B1

Reaction notes

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