Methyl iodide → HCID 178503984, compound

HRID 1861927Notes

Reaction equation

HRID 1861927 reaction equation
[C:1]([O:5][C:6](=[O:24])[NH:7][C:8]1([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([NH:20][C:21]([NH2:23])=[S:22])[CH:15]=2)[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)([CH3:4])([CH3:3])[CH3:2].[CH3:25]I>>[C:1]([O:5][C:6](=[O:24])[NH:7][C:8]1([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([NH:20][C:21](=[NH:23])[S:22][CH3:25])[CH:15]=2)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 22981119HCID 22981119, compound

Product 1

HCID 178503984HCID 178503984, compoundYield 70%

Procedure

Using the compound obtained in Example 140 as a starting material and also using methyl iodide as a reagent, reaction was performed as in Example 29 to give 85 mg of the titled compound (yield, 70%).

Workup

  1. customreaction

Sources & evidence

ORD record
ord-e9dcf8d534a546a582291f031909d522
Source dataset
uspto-grants-2003_03
Patent number
US06534546B1

Reaction notes

Loading…