Methyl iodide → HCID 178503983, compound

HRID 1861929Notes

Reaction equation

HRID 1861929 reaction equation
[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([NH:19][C:20]([NH2:22])=[S:21])[CH:14]=2)[CH2:12][CH2:11][CH2:10][CH2:9]1)([CH3:4])([CH3:3])[CH3:2].[CH3:24]I>>[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([NH:19][C:20](=[NH:22])[S:21][CH3:24])[CH:14]=2)[CH2:12][CH2:11][CH2:10][CH2:9]1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 22981120HCID 22981120, compound

Product 1

HCID 178503983HCID 178503983, compoundYield 94%

Procedure

Using the compound obtained in Example 149 as a starting material and also using methyl iodide as a reagent, reaction was performed as in Example 29 to give 82 mg of the titled compound (yield, 94%).

Workup

  1. customreaction

Sources & evidence

ORD record
ord-c038ba9cfb9c42d78d9cf9af40f20fa4
Source dataset
uspto-grants-2003_03
Patent number
US06534546B1

Reaction notes

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