Trifluoroacetic acid → HCID 18621214, compound

Participants

Reaction Steps

To a solution of product from Step D (2.30 g, 3.69 mmol) in methylene chloride (16 mL) was added trifluoroacetic acid (4 mL). The resulting solution was stirred for 3 hours, then poured onto saturated aqueous sodium bicarbonate, and extracted with methylene chloride (3×50 mL). The combined organic layers were dried over sodium sulfate, filtered, and concentrated in vacuo to provide the title product as a yellow oil which was sufficiently pure for use in the next step.

Provenance & Evidence