HuagongsheHuagongshe Chemistry Print Report · For research reference only
Anthranilic Acid → Acetanthranil
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Anthranilic Acid | HCID 227 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Product | Acetanthranil | HCID 68236 | — |
Reaction Steps
Anthranilic acid (274.3 g) and acetic anhydride (1.1 L) were combined then heated at reflux for 3.5 hours. The reaction mixture was concentrated under vacuum. The residue was combined with methanol (550 mL) then concentrated under vacuum to provide 2-methyl-4-oxo-3,1-benzoxazine as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06534654B2 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-e2fb55d1443d4341b367173f0c07e7d4 |
| Source note | uspto-grants-2003_03 |