Tetrahydrofuran → HCID 69527272, compound

Participants

Reaction Steps

Trimethylphosphine (50.0 ml of a 1.0 molar solution in tetrahydrofuran, 5.00×10−2 mol) was added via addition funnel over about 2 minutes into a thoroughly nitrogen degassed dispersion of vinylbenzyl bromide (9.85 g, 5.00×10−2 mol) in diethyl ether (100 ml). A solid precipitate began to form almost immediately. The reaction was allowed to stir for 4 hours at room temperature, then was placed in a freezer overnight. The solid product was isolated by filtration, washed three times with 100 ml of diethyl ether, and dried under vacuum for 2 hours. Pure product (11.22 g) was recovered as a white powder (82.20% yield).

Provenance & Evidence