1,3-Cyclopentanedione → HCID 9967386, compound

Participants

Reaction Steps

2-Nitrothiophene-4-carboxaldehyde (0.16 g, 1.0 mmol), 1,3-cyclopentadione (0.1 g, 1.0 mmol), and 5-amino-1-methyl-1,2-dihydropyrazol-3-one (0.11 g, 1.0 mmol) were processed as described in Example 1 to provide 0.24 g of the title compound. 1H NMR (300 MHz, DMSO-d6) δ 2.35 (m, 2H), 2.68 (m, 2H), 3.5 (s, 3H), 4.8 (s, 1H), 7.51 (d, 1H), 7.89 (d, 1H), 9.75 (bs, 1H), 10.47 (s, 1H); MS (ESI−) m/z 331 (M−H)−; Anal. calcd for C4H12N4O4S: C, 50.60;H, 3.64; N, 16.86. Found: C, 51.06;H, 3.68; N, 16.97.

Provenance & Evidence