HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 23500384, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Phloroglucinol | HCID 359 | — |
| Reactant | Ethyl 2-cyclopentyl-3-oxobutanoate | HCID 17750296 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 23500384 | HCID 23500384 | — |
Reaction Steps
A solution of phloroglucinol (2.00 g) and ethyl 2-cyclopentylaceto-acetate (3.14 g) in ethanol (40 ml) was treated with dry HCl at 0° C. for 2.5 hours and the solution kept at that temperature overnight. Solvent was evaporated and the precipitate purified with flash chromatography eluting with toluene-EtOAc-AcOH (8: 1:1). Yield 1.22 g (29%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06538022B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-6616317084a64be6b92f6be30396555a |
| Source note | uspto-grants-2003_03 |