反应详情

In 200 ml of dichloromethane, was dissolved 9.05 g of the compound obtained in Example 1, 2 or 3. To the resulting solution, was added 20.6 g of manganese dioxide. The obtained mixture was stirred at room temperature for 40 hours. The reaction solution was filtered through Celite, and the Celite was further washed with dichloromethane. Each filtrate was combined into one portion, and the solvent was removed under reduced pressure to afford 7.65 g (85%) of the title compound as a white crystal.

1. filtrationThe reaction solution was filtered through Celite
2. washthe Celite was further washed with dichloromethane
3. customthe solvent was removed under reduced pressure