HCID 11063236, compound → ETHYL (1-CYANOCYCLOHEXYL)ACETATE

HRID 1862576Notes

Reaction equation

HRID 1862576 reaction equation
[CH2:1]([O:3][C:4](=[O:14])[CH2:5][C:6]1([C:12]#[N:13])[CH:11]=[CH:10][CH2:9][CH:8]=[CH:7]1)[CH3:2]>[Pd].CO>[CH2:1]([O:3][C:4](=[O:14])[CH2:5][C:6]1([C:12]#[N:13])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)[CH3:2]

Participants

4

Reactant 1

HCID 11063236HCID 11063236, compound

Product 1

HCID 10965422ETHYL (1-CYANOCYCLOHEXYL)ACETATEYield 94.3%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Added 1% Pd/C catalyst (1.67 g, 0.157 mmol) to a solution of (1-cyanocyclohexa-2,5-dienyl)acetic acid ethyl ester (3.00 g, 15.7 mmol) in MeOH (75 mL). After shaking the reaction under 20 psi H2 at room temperature for 2 hours, the pressure was slowly released. The reaction was filtered and concentrated under reduced pressure to afford 2.89 g (94%) of product as an oil.

Workup

  1. customthe reaction under 20 psi H2 at room temperature for 2 hours
  2. filtrationThe reaction was filtered
  3. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-a26f848a323241d9b785d8e9c5cd2aae
Source dataset
uspto-grants-2003_03
Patent number
US06538148B2

Reaction notes

Loading…