Sodium Hydroxide → (1-Cyanocyclohexyl)acetic acid

HRID 1862577Notes

Reaction equation

HRID 1862577 reaction equation
C([O:3][C:4](=[O:14])[CH2:5][C:6]1([C:12]#[N:13])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)C.[OH-].[Na+]>>[C:12]([C:6]1([CH2:5][C:4]([OH:14])=[O:3])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)#[N:13]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 10965422ETHYL (1-CYANOCYCLOHEXYL)ACETATE

Product 1

HCID 11073797(1-Cyanocyclohexyl)acetic acid

Procedure

(1-Cyanocyclohexyl)acetic acid ethyl ester is reacted with aqueous sodium hydroxide solution using the methodology disclosed at Column 15, Method C, Step B of U.S. Pat. No. 5,132,451 which is herein incorporated by reference to afford the title product.

Sources & evidence

ORD record
ord-10201224fd264bd183820216bf6f4c29
Source dataset
uspto-grants-2003_03
Patent number
US06538148B2

Reaction notes

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