HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Benzyloxy-5-[2-(p-toluenesulfonyloxy)ethyl]benzamide → Benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Benzyloxy-5-[2-(p-toluenesulfonyloxy)ethyl]benzamide | HCID 18620113 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Benzamide | HCID 2331 | 260.5% |
Reaction Steps
2-Benzyloxy-5-[2-(p-toluenesulfonyloxy)ethyl]benzamide (627 mg) was dissolved in methanol (5 ml) and tetrahydrofuran (5 ml), and 10% palladium carbon (wet, 50% water) (169 mg) was added to the solution. The mixture was stirred for 1 hour at room temperature under a hydrogen atmosphere, and the catalyst was filtered off. Removal of the solvent under reduced pressure gave 2-hydroxy-5-[2-toluenesulfonyloxy)ethyl]benzamide (465 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06538152B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-dc26481754074cf99fd4dc34845ef5ad |
| Source note | uspto-grants-2003_03 |