HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 4-(Imidazo[1,2-a]pyridin-3-yl)piperidine di-TFA salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Tert-butyl 4-(imidazo[1,2-a]pyridin-3-yl)piperidine-1-carboxylate | HCID 21912736 | — |
| Product | 4-(Imidazo[1,2-a]pyridin-3-yl)piperidine di-TFA salt | HCID 131723148 | — |
Reaction Steps
To 100 mg of 1-(t-butoxycarbonyl)-4-(imidazo[1,2-a]pyridin-3-yl)piperidine from Step A was added 2 mL TFA. The reaction was stirred at rt for 1 h. The mixture was concentrated under reduced pressure to afford 180 mg of a viscous oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06538002B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-87ab71a28f4a44258c3d2623d97d0a38 |
| Source note | uspto-grants-2003_03 |