反应详情

温度

6 °C

To a chilled (6° C.) solution containing 31.8 g (0.2 mole) of the ether prepared as in (a) above and 28.7 g of acetic anhydride in 200 ml of glacial acetic acid was added dropwise a solution of 13.9 g (0.22 mole) of 90% nitric acid in 100 ml of glacial acetic acid. The reaction mixture was allowed to stand at ambient temperature for 12 hours, poured into water and extracted with methylene chloride. The extract was washed with 5% sodium carbonate, water, dried, and concentrated to give 21.8 g of product as an amber oil.

1. additioncontaining
2. extractionextracted with methylene chloride
3. washThe extract was washed with 5% sodium carbonate, water
4. customdried
5. concentrationconcentrated