反应详情

3-Methyl-5-trichloromethyl-1,2,4oxadiazole (43 g, 0.21 mole) was added to n-butylamine (46.75 g, 0.63 mole) and stirred at room temperature overnight. Excess amine was removed under vacuum and the residue distilled (oil bath 110° C./0.5 mmHg). Recrystallisation from petroleum ether 60°-80° C. gave the title compound as white plates 26 g, m.p. 62°-65° C.

1. customExcess amine was removed under vacuum
2. distillationthe residue distilled (oil bath 110° C./0.5 mmHg)
3. customRecrystallisation from petroleum ether 60°-80° C.