Acetic Anhydride → HCID 12803438, compound

HRID 1862813Notes

Reaction equation

HRID 1862813 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:7][C:6]1=[O:16].[C:17](OC(=O)C)(=[O:19])[CH3:18]>>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:7]([C:17](=[O:19])[CH3:18])[C:6]1=[O:16]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 12803422HCID 12803422, compound

Product 1

HCID 12803438HCID 12803438, compound

Procedure

Approximately 21.8 g of 1-(2-methoxyethyl)-4-phenyl-4-imidazolin-2-one and 120 ml. of acetic anhydride is refluxed together for four hours. The acetic anhydride is distilled out at reduced pressure. The residual semisolid is recrystallized from ethyl acetate to yield the title compound Formula (2) in Sequence 2 as a white solid; m.p. 81°-82° C.

Workup

  1. distillationThe acetic anhydride is distilled out at reduced pressure
  2. customThe residual semisolid is recrystallized from ethyl acetate

Sources & evidence

ORD record
ord-98c65746f25e4253966862d213adcecd
Source dataset
uspto-grants-1979_09
Patent number
US04166824

Reaction notes

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