Water → HCID 86736630, compound

Participants

Reaction Conditions

Reaction Steps

4-Azido-3-carbethoxyquinoline (1.4 g; 0.006 M) was suspended in 10% aq. NaOH at ambient temperatures and the mixture stirred until complete solution had been obtained. The solution was filtered, cooled to 0° C. and acidified to pH 4 with 5 M HCl. The resulting precipitate was filtered, washed well with H2O and dried in vacuo over P2O5 to yield the product, 1.3 g (93%), as a monohydrate, m.p. 284° C. (dec.) (Found: N, 24.53%, C10H8N4O3 requires: N, 24.46%), νmax (nujol) 3200-3700(br), 2200-2600(br), 2110, 1700, 1492, 1327, 1215, 760cm-1, δ[(CD3)2SO] 7.45-3.1(m), 8.9(s) (aromatic protons). 14-16 (broad) (CO2H*+H2O),

Provenance & Evidence