Ammonia → HCID 20393842, compound

HRID 1862828Notes

Reaction equation

HRID 1862828 reaction equation
N.[NH2:2][CH:3]1[CH2:8][N:7]([CH3:9])[CH2:6][CH2:5][N:4]1[C:10]1[N:15]=[CH:14][C:13]([S:16][CH3:17])=[C:12]([Cl:18])[N:11]=1>C(O)C>[ClH:18].[NH2:2][CH:3]1[CH2:8][N:7]([CH3:9])[CH2:6][CH2:5][N:4]1[C:10]1[N:15]=[CH:14][C:13]([S:16][CH3:17])=[C:12]([Cl:18])[N:11]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 20393834HCID 20393834, compound

Product 1

HCID 20393842HCID 20393842, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In the same way as in Example 1, but replacing the ethylamine by ammonia, 2-amino-4-N-methylpiperazino-6-chloro-5-methylthio-pyrimidine is prepared. M.p. 191°-192° C. (ethanol).

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-92d9f53da5f24988b1a08c5af07c0955
Source dataset
uspto-grants-1979_09
Patent number
US04166852

Reaction notes

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