HuagongsheHuagongshe Chemistry Print Report · For research reference only
M-Cresol → HCID 178433662, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | M-Cresol | HCID 342 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine dihydrochloride | HCID 215819 | — |
| Reactant | HCID 178425733 | HCID 178425733 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 178433662 | HCID 178433662 | — |
Reaction Steps
4.94 g. (0.249 mole) 5-methyl-4-(2-aminoethyl) imidazole dihydrochloride is converted to the free base with NaOH. The free base is combined with 4.36 g. (0.0249 mole) of O-m-tolyl-N-cyanoisourea in 63 ml. isopropanol. This mixture is refluxed for one hour. The mixture is then cooled to room temperature, filtered to remove insoluble material, and the solvent is evaporated to obtain a cloudy oil of the product mixed with m-cresol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04166860 |
| Source dataset | uspto-grants-1979_09 |
| ORD ID | ord-e42112a5cade4e968931eb96eaf9b353 |
| Source note | uspto-grants-1979_09 |