2-Bromobutane → HCID 20394007, compound

Participants

Reaction Steps

12 g of 7-hydroxy-isoflavone are boiled for 2 hours under reflux condenser with 10 g of potassium carbonate and 9 g of sec-butyl bromide in 40 ml of dimethyl formamide. On pouring the reaction mixture on water, the separated product is recrystallized from acetone, yielding 12 g of 7-sec-butyloxy-isoflavone, m.p. 87°-89° C. In a similar way, also 7-sec-butyloxy-2-methyl-isoflavone, m.p. 107°-109° C., and all the other isoflavone derivatives described in Example 7 can be prepared.

Provenance & Evidence