Acetic Anhydride → HCID 20393546, compound

HRID 1862921Notes

Reaction equation

HRID 1862921 reaction equation
[OH:1][CH:2]([CH2:37][NH:38][CH:39]1[CH2:44][C:43]([CH3:46])([CH3:45])[N:42]([CH3:47])[C:41]([CH3:49])([CH3:48])[CH2:40]1)[CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH:22]([OH:36])[CH2:23][NH:24][CH:25]3[CH2:30][C:29]([CH3:32])([CH3:31])[N:28]([CH3:33])[C:27]([CH3:35])([CH3:34])[CH2:26]3)=[CH:16][CH:15]=2)([CH3:13])[CH3:12])=[CH:7][CH:6]=1.C(O[C:54](=[O:56])[CH3:55])(=O)C>C1C=CC=CC=1>[C:2]([O:36][CH:22]([CH2:23][N:24]([CH:25]1[CH2:30][C:29]([CH3:32])([CH3:31])[N:28]([CH3:33])[C:27]([CH3:34])([CH3:35])[CH2:26]1)[C:54](=[O:56])[CH3:55])[CH2:21][O:20][C:17]1[CH:16]=[CH:15][C:14]([C:11]([C:8]2[CH:9]=[CH:10][C:5]([O:4][CH2:3][CH:2]([O:1][C:17](=[O:20])[CH3:16])[CH2:37][N:38]([CH:39]3[CH2:40][C:41]([CH3:49])([CH3:48])[N:42]([CH3:47])[C:43]([CH3:46])([CH3:45])[CH2:44]3)[C:5](=[O:4])[CH3:6])=[CH:6][CH:7]=2)([CH3:12])[CH3:13])=[CH:19][CH:18]=1)(=[O:1])[CH3:3]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 20393558HCID 20393558, compound

Product 1

HCID 20393546HCID 20393546, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 1 g of 2,2-bis[4-{2-hydroxy-3-[(1,2,2,6,6-pentamethyl-4-piperidyl)amino]propoxy}phenyl]propane, obtained as described in Example 4, and 1 g of acetic anhydride in 10 ml of benzene was reacted in a similar manner to that described in Example 8, giving the desired compound in the form of a white powder. The compound had an Rf value of 0.70 on thin layer chromatography on silica gel developed with a 9:1 by volume mixture of ethyl acetate and triethylamine.

Workup

  1. customobtained
  2. customwas reacted in a similar manner to that

Sources & evidence

ORD record
ord-3c07dcadec2440f9b15eb442f44749ae
Source dataset
uspto-grants-1979_09
Patent number
US04166813

Reaction notes

Loading…